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Amongst others The California Bureau of Medical Cannabis Regulation (Bureau) include our cannabis oil pages as âDocuments Relied Upon,â however, we are based in Europe.
The use of medical cannabis oil is not a new phenomenon; historians even suggest that the recipe for the anointing oil mentioned in the Bible included cannabis, or âkaneh-bosmâ in Hebrew.
It is only recently that the cannabinoids found within medical cannabis oil have been discovered to have anti-cancer possibilities in laboratory testing.
Cannabis was first listed in the 1851 (3rd edition) of the U.S. Pharmacopoeia and until prohibition was introduced cannabis was the primary treatment for over 100 separate illnesses and diseases.
There is an argument that even recreational users are to a certain extent self medicating with cannabis, as a means of relieving stress, stimulating appetite, regulating sleep patterns and improving their general outlook on life.
Canada and a large number of American states have now legalized medical marijuana use despite currently only 6% of studies carried out on medical cannabis oil being designed to evaluate and analyze its medicinal properties.
Rick Simpson is a Canadian cancer survivor who is now universally referred to as the man who rediscovered the cure for cancer.
In 2003 Rick was diagnosed with basal cell carcinoma skin cancer. He had discovered three cancerous sores on his body. Two on his face and one on his neck.
After conventional cancer treatments failed to improve his condition Rick decided to treat his diagnosis himself.
For almost a year Rick had been extracting the oil from the cannabis plant and ingesting it orally.
He had been taking the oil for other health reasons but the cancer diagnosis reminded him of something and gave him an idea.
He remembered a radio program he had listened to almost 30 years earlier and decided to ignore his oncologists objections and treat himself, as he reasoned that conventional treatment was simply not working.
The radio headline had stated that the University of Virginia had found that the cannabinoid in cannabis known as THC could kill cancer in mice.
Rick applied cannabis oil under some bandages. After 4 days of waiting he decided it was time to see if anything had happened under the bandages.
Rick is still cancer free and the medical profession now recognise the benefits of cannabis medication. This is due to the work, courage and conviction of one man.
Cannabis is often referred to by many different names including marijuana, ganja, weed or herb but regardless of how it is referred to cannabis is one of the safest medicines available today. There has never been a single recorded fatality from cannabis use in thousands of years of human history.
No one has ever died as a direct result of ingesting cannabis or indeed concentrated cannabis oil.
The estimated LD-50 (lethal threshold) for marijuana,established in 1988 by the DEAâs appropriate fact-finder, is 1:20,000 or 1:40,000.
At present it is estimated that marijuanaâs LD-50 is around 1:20,000 or 1:40,000. In layman terms this means that in order to induce death a marijuana smoker would have to consume 20,000 to 40,000 times as much marijuana as is contained in one marijuana cigarette. NIDA-supplied marijuana cigarettes weigh approximately .9 grams.
A smoker would theoretically have to consume nearly 1,500 pounds of marijuana within about fifteen minutes to induce a lethal response.
Heroin has a therapeutic ratio of 6:1, alcohol and Valium 10:1. Cocaine 15:1. Aspirin has a therapeutic ratio of 20:1; twenty times the recommended dose (40 tablets) can cause death, and almost certainly induce extensive internal bleeding and serious injury.
Drugs used to treat patients with cancer, glaucoma and MS are all known to be highly toxic.
The ratio of some drugs used in antineoplastic treatments have therapeutic ratios below 1.5:1.
“Although patients with cancer may derive much benefit from treatment, they are at risk for developing life-threatening complications.
Hypersensitivity reactions can be severe, as in the case of anaphylaxis with L-asparaginase.
Cardiac toxicities consist of arrhythmias with various drugs, hemorrhagic myocarditis with cyclophosphamide and ifosfamide, cardiomyopathy with anthracyclines, and pericardial disease.
Acute respiratory failure may occur as a result of ARDS caused by ATRA or cytarabine, from interstitial fibrosis, or from pulmonary veno-occlusive disease.
Hemorrhagic cystitis caused by cyclophosphamide and ifosfamide can be severe and result in exsanguination if unresponsive to treatment.
Disseminated intravascular coagulation and thrombotic microangiopathy can produce thrombotic or hemorrhagic complications.
Gastrointestinal toxicities include significant hepatotoxicity with a variety of drugs and development of acute surgical abdomen.” – ProfessorÂ Carl B. Shanholtz, MD.
ResearchÂ showed that cancer drugs are killing up to 50 per cent of patients in some hospitals.
For the first time researchers looked at the numbers of cancer patients who died within 30 days of starting chemotherapy, which indicates that the medication is the cause of death, rather than the cancer.
The study by Public Health England and Cancer Research UK found that across England around 8.4 per cent of patients with lung cancer, and 2.4 per cent of breast cancer patients died within a month.
But in some hospitals the figure was far higher. In Milton Keynes the death rate for lung cancer treatment was 50.9 per cent.
Chemotherapy is toxic for the body because it does not discriminate between healthy and cancerous cells.
The researchers also found that there were significant differences in survival for older people and those in poorer health. They advised doctors to be more careful in selecting patients for treatment where it could do more harm than good.
Researchers looking for risk factors of heart disease tested the lung function of 5,115 young adults over the course of 20 years Tobacco smokers lost lung function over time, but cannabis users actually showed an increase in lung capacity.
Itâs possible that the increased lung capacity maybe due to taking a deep breaths while inhaling the drug and not from a therapeutic chemical in the drug.
The principal cannabinoids in the cannabis plant include tetrahydrocannabinol (THC) cannabidiol (CBD) and cannabinol (CBN).
cannabis-THCTHC is the primary psychoactive compound along with CBD, a non-psychoactive compound.THC Has been shown to kill cancer cells in laboratory trials.
CBD may ease THC-induced anxiety or psychosis and their combination results in a more satisfying effect.
CBD has also been shown to have anti-cancer properties in laboratory tests.
The cannabis plant and its products consist of an enormous variety of chemicals.
Some of the 483 compounds identified are unique to cannabis, for example, the more than 60 cannabinoids, whereas the terpenes, with about 140 members forming the most abundant class, are widespread in the plant kingdom
The cannabis plant is literally an organic chemical factory.
In some medical cannabis oil preparations THC levels have risen radically by using a concentrating process such as butane hash oil that yields levels in excess of 80% cannabinoid content.
If marijuana were unknown, and bio prospectors were suddenly to find it in some remote mountain crevice, its discovery would no doubt be hailed as a medical breakthrough. Scientists would praise its potential for treating everything from pain to cancer, and marvel at its rich pharmacopoeia - many of whose chemicals mimic vital molecules in the human body - The Economist.
If alcohol were discovered today it would probably be outlawed - David Nutt, former chief drugs advisor to the UK Government.
Medical cannabis oil is consumed by various means, with the most common being smoking, followed by vaporization, and then by the oral route. Medical cannabis oil is generally taken orally.
Standard medicines are not delivered as inhaled smoke, but enter the body by other routes of administration (pill, injection, topical creams, patches, inhalants, eye drops, liquid drinks, suppositories)
When used to prevent nausea, factors such as speed of brain entry and challenges of swallowing whilst vomiting are important when considering inhaling cannabis smoke as a medicine.
Vaporisation of medical cannabis oil releases maximal levels of THC into blood within minutes, peaking at 15-30 minutes, and decreasing within 2-3 hours.
Increasingly, delivery of cannabis to the brain for medical or recreational use is via cannabis vaporization.
Lower temperatures in the vaporization of cannabis deliver fewer high molecular weight components.
Heating cannabis at moderate temperatures with a commercially available vaporizer produces a fine mist of cannabis vapors that can also be inhaled via electronic cigarettes, reducing exposure to pyrolytic byproducts.
While vaporizers have risen in popularity in recent years, their effects have not yet been investigated by large-scale studies
One study published by Dr. Earleywine in 2007, suggested that cannabis can be âsaferâ when a vaporizer is used and may decrease possible respiratory issues, which doesnât make much sense considering other studies that found lung capacity was unaffected by cannabis use.
Vaporization does however reduce the characteristic odor of cannabis smoke, enabling medical users to be far more discreet in their administration.
medical cannabis oil cancer sucessResearchers have found medical cannabis oil helps fight Breast Cancer, this cancer comprises 10.4% of all cancer incidence among women, making it the second most common type of non-skin cancer (after lung cancer).
It is the fifth most common cause of cancer death. In 2004, breast cancer caused 519,000 deaths worldwide 7% of cancer deaths; almost 1% ofâ¦ 855-536-8386
Cannabis terpenoids and flavonoids may also increase cerebral blood flow, enhance cortical activity, kill respiratory pathogens, and provide anti-inflammatory activity.
Cannabis terpenoids share a precursor to cannabinoids (e.g. limonene, myrcene, Î±-pinene, linalool), some of which are thought to be suitable for therapies or as facilitators of cannabinoid efficacy.
Cannabinoids are not the only products of the cannabis plant with medicinal properties.
Evidence is needed to prove the validity of the widely held belief that whole plant cannabis is superior to isolated compounds because of synergism between various components.
However, it does make sense that using the whole spectrum of cannabinoids is preferable to isolating specific components such as CBD.
Preparations of cannabis oil generally contain a full cannabinoid profile.
(AD) is the most common type of dementia, and is characterized by a number of debilitating symptoms, including cognitive decline, sleep disorders, and behavioural changes.
A study led by Kim Janda of the Scripps Research Institute suggests marijuana may be able to slow the progression of Alzheimerâs disease.
The 2006 study, published in the journal Molecular Pharmaceutics, found that THC, the active chemical in marijuana, slows the formation of amyloid plaques by blocking the enzyme in the brain that makes them. There is potential for sedative effects and the degenerative process.
A recent, international survey was carried out of 31 countries and investigated the medicinal use of cannabis in the United States, Germany, Canada, France, the Netherlands and Spain.
They found that cannabis was used primarily for:
THC binds to receptors in the nerves and muscles to relieve pain Other studies suggest that the chemical also helps control the muscle spasms. Other types of muscle spasms respond well to cannabis use.
Pain can be classified as acute or chronic, or by site of origin (nociceptive) or nerves (neuropathic).
Neuropathic pain occurs in various disease states (e.g. diabetes, HIV/AIDS, post-traumatic pain, cancer, excess alcohol use, rheumatoid arthritis etc.) and can be a persistent, debilitating condition.
HIV neuropathic pain affects 30% or more of HIV-infected individuals and some antiretroviral therapies can worsen the condition. Current analgesics and other medications offer incomplete pain relief when compared to medical cannabis oil use.
Many HIV-infected individuals report improvements in health from smoking cannabis. Of over 200 people with HIV/AIDS, 23% reported use of cannabis for pain relief in the previous month.
In 2010, researchers at Harvard Medical School suggested that that some of the drugâs benefits may actually be from reduced anxiety, which would improve the smokerâs mood and act as a sedative in low doses.
Cannabis use can prevent epileptic seizures, a 2003 study showed. Robert J. DeLorenzo, of Virginia Commonwealth University, gave marijuana extract and synthetic marijuana to epileptic rats.
The drugs rid the rats of the seizures for about 10 hours.
Cannabinoids like the active ingredients in marijuana, tetrahydrocannabinol (THC), control seizures by binding to the brain cells responsible for controlling excitability and regulating relaxation.
The findings were published in the Journal of Pharmacology and Experimental Therapeutics.
THC-like compounds made by the body increase the permeability of the intestines, allowing in bacteria.
The plant-derived cannabinoids in marijuana block these body-cannabinoids, preventing this permeability and making the intestinal cells bond tighter together.
In clinical tests patients reported after eight weeks of treatment and two weeks thereafter that complete remission was achieved. A positive clinical response was observed in 10 of 11 subjects in the cannabis group.
There are many health benefits associated with the use of medical cannabis oil. Cannabis oil has been shown to help veterans suffering from PTSD. The Department of Health and Human Services recently signed off on a proposal to study marijuanaâs potential as part of treatment for veterans with post-traumatic stress disorder. In New Mexico,
PTSD is the number one reason to be granted a license for medical marijuana, but this is the first time the U.S. government has approved a proposal that incorporates smoked or vaporized marijuana, which is currently classified by the government as a drug with no accepted medical applications.
Naturally occurring cannabinoids, similar to THC, help regulate the system that causes fear and anxiety in the body and brain. Interestingly, the high from THC is also associated with temporary impairments of memory.
Recent studies confirm that oral doses of THC can help relieve a variety of PTSD-related symptoms including flashbacks, agitation and nightmares.
Research from the University of Nottingham shows that cannabis may help protect the brain from damage caused by stroke.
By reducing the size of the area affected by the stroke in rats, mice, and monkeys.
This isnât the only research that has shown neuroprotective effects from cannabis.
Some research shows that the plant may help protect the brain after other traumatic events, like concussions. There is some evidence that cannabis can help heal the brain after a concussion or other traumatic injury.
A recent study in the journal Cerebral Cortex showed that in mice, cannabis oil lessened the bruising of the brain and helped with healing mechanisms after a traumatic injury.
The medical benefits of cannabis continue to be debated globally, as they have been for nearly 150 years but the evidence tends to support the fact that medical cannabis oil has many therapeutic effects and its continued prohibition denies many patients a viable alternative to pharmaceutical drugs.